Sitagliptin (Sitagliptin phosphate)

Common use

Sitagliptin is prescribed to manage type 2 diabetes mellitus. It works by inhibiting the DPP-4 enzyme, which increases incretin hormone levels. This helps the body release more insulin after meals, reduces glucagon production, and supports better blood sugar control.

Dosage and direction

Sitagliptinis usually taken once daily with or without food. Tablets should be swallowed whole. The dose is determined by the healthcare provider based on kidney function and individual patient needs. It may be prescribed alone or with other diabetes medications such as metformin, sulfonylureas, or insulin.

Precautions

Inform your doctor if you have kidney disease, pancreatitis, liver problems, or a history of heart failure. Maintain a healthy diet and exercise routine as part of diabetes management. Report any symptoms such as severe abdominal pain or unexplained fatigue.

Contraindications

Do not use Sitagliptinif allergic to sitagliptin or any component of the tablet. It is not indicated for type 1 diabetes or diabetic ketoacidosis.

Possible side effect

Common side effects include headache, nasopharyngitis, upper respiratory infection, and mild gastrointestinal discomfort. Serious side effects may include pancreatitis, severe allergic reactions, joint pain, or low blood sugar (especially when combined with other diabetes medications). Seek medical attention if serious symptoms occur.

Drug interaction

Sitagliptinmay interact with other antidiabetic drugs, ACE inhibitors, digoxin, or certain immunosuppressants. Inform your doctor about all prescription drugs, over-the-counter medications, and supplements you are taking.

Missed dose

If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose.

Overdose

Overdose may cause hypoglycemia, nausea, vomiting, or dizziness. Seek immediate medical attention if an overdose is suspected.

Storage

Store Sitagliptinat room temperature, away from heat, moisture, and light. Keep tablets in the original container and out of reach of children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.